A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Anti-angiogenic ophthalmic agents act as vascular endothelial growth factor (VEGF) antagonists. When retinal pigment cells become ischemic and dry up VEGF stimulates generation of new blood vessels by a process called neovascularization. During the generation of new blood vessels in the retina, if the blood vessels do not generate properly it causes leaking. This can lead to loss of vision.
Anti-angiogenic ophthalmic agents are used to stop neovascularization in age related macular degeneration.
See also
Medical conditions associated with anti-angiogenic ophthalmic agents:
- Diabetic Retinopathy
- Macular Degeneration
- Macular Edema
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